Applications of Liquid Handling Robots

Applied Tech Review | Monday, October 11, 2021

Liquid handling robots are being used in various areas as they can pipette liquids precisely and quickly, eliminating the need for human labor and reducing the cost of chemicals needed.

Fremont CA: In a laboratory context, liquid handling robots are automated equipment that distributes and sample liquids. Automated pipetting systems and microplate washers are examples of such systems. While maintaining high precision, these devices eliminate the need for human labor to prepare high throughput screening or sequencing, liquid weighing, sample preparation, and bioassays.

In both industrial and academic settings, liquid handling robots are becoming more common. The robots can pipette liquids as little as 100 nL correctly and quickly, reducing the cost and volume of chemicals needed. Liquid handling robots are classified as either mobile or fixed substrate kinds, depending on how the substrate moves.

Applications of Liquid handling robots:

Pharma Industries

One of the important consumers of liquid handling robots is the pharmaceutical industry. Therapeutic development might entail screening millions of chemicals for prospective drug candidates, which can be time-consuming and costly if fragile bioactive assay samples are utilized. Liquid handling robots' ability to precisely manage the volume of liquid delivered can save firms a lot of money on supplies.

Biological research

Liquid handling robots can be beneficial in biological research and drug development labs, where automated systems can assist reduce contamination and carry out the numerous sampling, mixing, and pipetting stages required in such studies.

Epigenetics and genetics

Robots that handle liquids have become increasingly popular in epigenetics and genetics research. Several second-generation sequencing technologies and automated methods have been developed for PCR reaction preparation phases, as well as liquid handling and immunoprecipitation stages in ChIP analysis. Liquid handling robots provide a potential alternative for enabling more epigenetic-based illness therapies, such as leukaemia and lymphoma.

Molecular biology assays

Antibody-based assays, molecular assays, and crystallography are some of the other areas of investigation. In some circumstances, automated systems are preferable to manual alternatives. The accuracy and reproducibility of pipetting can influence PCR findings because of the significant amplification differences it can cause. With manual pipetting, accuracy and reproducibility are challenging to achieve, but liquid handling robots make it much easier.

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